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What causes spina bifida?

Spina bifida is caused by abnormal folding of cells during the early stages of an embryo's development (embryogenesis). The exact reason why this occurs is unknown, but genetic and nutritional factors, particularly lack of folate during early pregnancy, appear to be involved.

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About this article

Author: Dr Idan Ben-Barak PhD, MSc, BSc (Med)
First answered: 07 Oct 2014
Last reviewed: 19 May 2018
Rating: 4.8 out of 5
Votes: 753 (Click smiley face below to rate)
Category: Fetal alcohol syndrome

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