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What causes scleroderma?

Scleroderma is caused by an autoimmune reaction. When operating correctly, the immune system helps your body fight off the infections. During an autoimmune reaction, the immune system mistakenly attacks healthy tissues. In scleroderma, excess collagen is produced in response to the damage. Collagen is a strong protein that gives strength to the skin and most tissues in the body. The excess collagen is deposited in the skin and organs, which leads to them becoming thickened and hard.13665

Author: Bow Tauro
First answered: 16 Jul 2015
Last reviewed: 19 May 2018
Rating: 5.0/5 Votes: 163

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