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What causes cystic fibrosis?

In cystic fibrosis a gene called CFTR, which plays a vital role in mucus production, is faulty. The gene makes the CFTR protein which is essential for balancing the salt concentration in the body's cells. When it does not work properly, the cells that produce the mucus do not secrete enough water, resulting in mucus that is dense, thick and sticky.

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About this article

Author: Dr Joanne Van der Velden PhD, BSc (Hons)
First answered: 18 Sep 2014
Last reviewed: 19 May 2018
Rating: 4.6 out of 5
Votes: 836 (Click smiley face below to rate)
Category: Bronchitis


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